Gomes Lab

Proteasome subunit binding to Ubiquitin

Muscle Physiology and

Proteomics Laboratory

Welcome to the Gomes Lab where we are interested in the molecular mechanisms of signal transduction, particularly in the role of proteostasis (protein homeostasis) in cardiovascular disease.  The two main research areas in my laboratory are: the role of the proteasome and immunoproteasome in normal, protected and diseased cardiac and skeletal muscles and the role of troponin in calcium regulation of muscle contraction in hypertrophic, dilated and restrictive cardiomyopathies.

The ubiquitin-proteasome system is the primary mechanism of protein degradation in all cells. A multifaceted experimental approach is being utilized to investigate the proteasome and troponin complexes.

176 Briggs Hall,

Department of Neurobiology, Physiology and Behavior

One Shields Avenue,

Davis,

CA 95616

 

Lab Phone: 530-754-9548

Contact Information:

Pictures of University of California, Davis Campus

Department of Neurobiology, Physiology and Behavior (NPB), College of Biological Sciences                   and Department of Physiology and Membrane Biology, School of Medicine