Gomes Lab |
Proteasome subunit binding to Ubiquitin |
Muscle Physiology and Proteomics Laboratory |
Welcome to the Gomes Lab where we are interested in the molecular mechanisms of signal transduction, particularly in the role of proteostasis (protein homeostasis) in cardiovascular disease. The two main research areas in my laboratory are: the role of the proteasome and immunoproteasome in normal, protected and diseased cardiac and skeletal muscles and the role of troponin in calcium regulation of muscle contraction in hypertrophic, dilated and restrictive cardiomyopathies. The ubiquitin-proteasome system is the primary mechanism of protein degradation in all cells. A multifaceted experimental approach is being utilized to investigate the proteasome and troponin complexes. |
176 Briggs Hall, Department of Neurobiology, Physiology and Behavior One Shields Avenue, Davis, CA 95616
Lab Phone: 530-754-9548 |
Contact Information: |
Pictures of University of California, Davis Campus |
Department of Neurobiology, Physiology and Behavior (NPB), College of Biological Sciences and Department of Physiology and Membrane Biology, School of Medicine |